Motivated by a desire to narrate and contextualize the deluge of "French theory," After the Deluege showcases recent work by today's brightest scholars of French intellectual history that historicizes key debates, figures, and turning points in the postwar era of French thought.

The interdisciplinary relevance of Spinoza today.

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Diacritics 31.1 (2001) 56-72 [Access article in PDF] Deconstruction and ZionismJacques Derrida's Specters of Marx Christopher Wise No differance without alterity, no alterity without singularity, no singularity without here-now. —Jacques Derrida, Specters of Marx Introduction Following Jacques Derrida's first sustained critique of Marx and Marxism in Specters of Marx: The State of the Debt, the Work of Mourning, and the New International (1994), an expanded version of his (...) lectures delivered at the University of California, Riverside, in May 1993, numerous "Marxist" theorists have responded to his provocative (and, for some, "untimely") intervention. Several of these critical responses have been gathered in Michael Sprinker's volume Ghostly Demarcations: A Symposium on Jacques Derrida's "Specters of Marx" (1999), which includes contributions from such diverse theorists as Pierre Macherey, Antonio Negri, Fredric Jameson, Terry Eagleton, Aijaz Ahmad, and many others. Important omissions from Sprinker's book include Gayatri Chakravorty Spivak's "Ghostwriting" (1995), an essay that Derrida nonetheless comments upon in his response "Marx & Sons," or any other feminist analysis of Specters of Marx, a curious absence in a text so riveted by questions of patriarchal affiliation. An even more startling omission from Sprinker's book is any analysis of Derrida's discussion of the Middle East, especially his remarks on the State of Israel and "a certain Jewish [i.e. Zionist] discourse on the Promised Land" [Specters of Marx 60] ("un certain discours juif de la Terre" [Spectres de Marx 104]). The myopic range of Marxist critiques of Specters of Marx is regrettable insofar as both Derrida and his Marxist critics ostensibly offer "radical" or "oppositional" perspectives on George H. W. Bush's New World Order while ignoring imperialist practices in places like Jerusalem, Golan Heights, the West Bank, and the Gaza Strip. In The End of the Peace Process (2001), Edward W. Said observes, "[w]hen one considers the broad lines of Jewish philosophy from [Martin] Buber to [Emmanuel] Levinas and perceives in it an almost total absence of reflection on the ethical dimensions of the Palestinian issue, one realizes how far one has to go" [208]. Said does not include Derrida in this trajectory of Jewish philosophers, possibly because Derrida has repeatedly disavowed any explicit affiliation with Judaism as religion, but I will argue here that Derrida's disavowal is implausible if not altogether disingenuous. In Ghostly Demarcations, Marxist responses to Derrida reveal how little real progress has been made in Western literary theory since the early 1980s, when now-tired debates about the Yale School echoed in nearly every humanities' corridor in the [End Page 56] United States. There are surely more compelling reasons to read Derrida today than to settle old scores with Ithaca-Irvine varieties of deconstruction. A key goal of this article is to enunciate Derrida's elision of the Palestinian question, not so much to undermine Specters of Marx, but to extend its power by venturing into domains that Derrida himself refuses to explore, a factor that weakens without totally disabling his deconstruction of Marxist theory. 1 The Rhetoric of Alterity In Specters of Marx, Derrida offers a complex, challenging, and virtuostic evaluation of Marx, focusing largely on "The Communist Manifesto" and The German Ideology. In particular, Derrida fixes his attention upon Marx's hostile and allegedly "obsessive" critique of Max Stirner, a rival Hegelian and "egological" anarchist. Derrida's criticisms of Marx turn on questions of spectrality, a suggestive way of describing the process whereby alienated or reified objects project illusory autonomy back upon the human subject. For purposes of the present essay, I draw attention to the rhetorical dimensions of the exchange between Derrida and his Marxist interlocutors, rather than the many subtleties implied by their respective analyses of this "new" concept formation. Such a strategy is useful not only because Derrida himself relies upon it in his essay "Marx & Sons," but also because it reveals key assumptions held by Derrida about deconstruction's political value, especially in the Middle East. Various contributors to Sprinker's volume do an impressive job of analyzing Derrida's critique of spectrality, especially Jameson, Warren Montag... (shrink)

Never have the American people been lonelier, unhappier, or more in need of a swift reactionary kick in the pants. There is a better way to live--a way tested by history, a way that fulfills the deepest needs of the human spirit, and a way that promotes the pursuit of true happiness. That way is the reactionary way. In this irrepressibly provocative book, Michael Warren Davis shows you how to unleash your inner reactionary and enjoy life as God (...) intended it. In The Reactionary Mind, you'll learn: Why medieval serfs were probably happier than you are; Why we should look back fondly on the Inquisition; Why all "news" is fake news; How "conservatives" become "adagio progressives""--Provided by the publisher. (shrink)

One strategy for dealing with apparent cases of knowledge from falsehood is to deny that the knowledge actually is from a falsehood. Those endorsing such a move have suggested that cases of knowledge from falsehood are instead cases of knowledge despite falsehood. We here provide a dilemma for those wanting to reject the possibility of knowledge from falsehood. The dilemma is explained in part by examining recent attempts to deny that knowledge can be inferentially derived from falsehood.

When is a person justified in believing a proposition? In this paper, I defend a view according to which a person is justified in believing a proposition just in case the person’s evidence sufficiently supports the proposition and the person responsibly acquired and sustained the evidence that supports the proposition. This view overcomes a deficiency in a prominent theory of epistemic justification. As championed by Earl Conee and Richard Feldman, Evidentialism is a theory subject to counterexamples at the hands of (...) cases involving epistemic irresponsibility. I critically discuss such a case as put forward by Jason Baehr. After providing an argument that clarifies why the case is problematic for Evidentialism, I defend my argument from a response by Earl Conee. Then I develop a theory of epistemic justification capable of handling cases involving epistemic irresponsibility, and I defend this theory from evidentialist objections. (shrink)

In this dissertation, I argue for a new conception of the epistemic condition on moral responsibility.

Gottlob Frege (1848–1925) was unquestionably one of the most important philosophers of all time. He trained as a mathematician, and his work in philosophy started as an attempt to provide an explanation of the truths of arithmetic, but in the course of this attempt he not only founded modern logic but also had to address fundamental questions in the philosophy of language and philosophical logic. Frege is generally seen (along with Russell and Wittgenstein) as one of the fathers of the (...) analytic method, which dominated philosophy in English-speaking countries for most of the twentieth century. His work is studied today not just for its historical importance but also because many of his ideas are still seen as relevant to current debates in the philosophies of logic, language, mathematics and the mind. The Cambridge Companion to Frege provides a route into this lively area of research. (shrink)

Integrating large language models (LLMs) like GPT-4 into medical ethics is a novel concept, and understanding the effectiveness of these models in aiding ethicists with decision-making can have significant implications for the healthcare sector. Thus, the objective of this study was to evaluate the performance of GPT-4 in responding to complex medical ethical vignettes and to gauge its utility and limitations for aiding medical ethicists. Using a mixed-methods, cross-sectional survey approach, a panel of six ethicists assessed LLM-generated responses to eight (...) ethical vignettes.The main outcomes measured were relevance, reasoning, depth, technical and non-technical clarity, as well as acceptability of GPT-4’s responses. The readability of the responses was also assessed. Of the six metrics evaluating the effectiveness of GPT-4’s responses, the overall mean score was 4.1/5. GPT-4 was rated highest in providing technical (4.7/5) and non-technical clarity (4.4/5), whereas the lowest rated metrics were depth (3.8/5) and acceptability (3.8/5). There was poor-to-moderate inter-rater reliability characterised by an intraclass coefficient of 0.54 (95% CI: 0.30 to 0.71). Based on panellist feedback, GPT-4 was able to identify and articulate key ethical issues but struggled to appreciate the nuanced aspects of ethical dilemmas and misapplied certain moral principles.This study reveals limitations in the ability of GPT-4 to appreciate the depth and nuanced acceptability of real-world ethical dilemmas, particularly those that require a thorough understanding of relational complexities and context-specific values. Ongoing evaluation of LLM capabilities within medical ethics remains paramount, and further refinement is needed before it can be used effectively in clinical settings. (shrink)

Infantologies is a collective writing project designed to express and summarise important ideas, approaches and forms of advocacy in a short and condensed method, in order to present a network of d...

This is an obituary for Michael H. Robins.

In this paper we discuss ethical implications of the use of mobile phone apps in the control of the COVID-19 pandemic. Contact tracing is a well-established feature of public health practice during infectious disease outbreaks and epidemics. However, the high proportion of pre-symptomatic transmission in COVID-19 means that standard contact tracing methods are too slow to stop the progression of infection through the population. To address this problem, many countries around the world have deployed or are developing mobile phone apps (...) capable of supporting instantaneous contact tracing. Informed by the on-going mapping of ‘proximity events’ these apps are intended both to inform public health policy and to provide alerts to individuals who have been in contact with a person with the infection. The proposed use of mobile phone data for ‘intelligent physical distancing’ in such contexts raises a number of important ethical questions. In our paper, we outline some ethical considerations that need to be addressed in any deployment of this kind of approach as part of a multidimensional public health response. We also, briefly, explore the implications for its use in future infectious disease outbreaks. (shrink)

_Taking Religious Claims Seriously_ is a systematic, critical, and comprehensive study of the fundamental questions of the philosophy of religion: religious experience, the existence and nature of God, religious knowledge and truth, good and evil, immortality of the soul, religious diversity, religious claims about the person, faith, and the religious way of life. In this study the author seeks to capture the reality and meaning of the religious as such: What is the foundation of religion? Under what conditions is an (...) authentic religious way of life possible? His method of inquiry is phenomenological. The author begins his discussion with a general characterization of the basic features of all the literate and illiterate religions of the world. He then identifies the ideas, beliefs, and concerns which are common to these religions: What are the central claims of these religions? How did the various religions understand these claims? The author makes a serious attempt to clarify these claims and explore the possibility for a reconcilation between them. For him, the foundation of religion is the religious experience, and the essence of this experience consists in a serious, cognitive, and meaningful encounter with the Ultimate Being. This being is the ground of the world and human life. This book is a comparative, pluralistic study of the philosophy of religion. (shrink)

Michael Peters, Sonja Arndt & Marek TesarThis is a collective writing experiment of PESA members, including its Executive Committee, asking questions of the Philosophy of Education in a New Key. Co...

European Journal of Political Theory, Ahead of Print. How should responsibility be theorized in the context of the global climate crisis? This question is often framed through the language of distributive justice. Because of the inequitable distribution of historical emissions, climate vulnerability, and adaptation capacity, such considerations are necessary, but do not exhaust the question of responsibility. This article argues that climate change is a structural injustice demanding a theory of political responsibility. Agents bear responsibility not in virtue of their (...) individual causal contribution or capacity, but because they participate in and benefit from the carbon-intensive structures, practices, and institutions that constitute the global political and economic system. Agents take responsibility by engaging in collective political action to transform these structures that generate both climate hazards and unjust relationships of power. By incorporating distributive principles within a capacious conception of political responsibility, this framework advances the theory and practice of climate justice in two ways. First, adopting a relational rather than individualistic criterion of responsibility better makes sense of how and why individuals bear responsibility for a global and intergenerational injustice like climate change. Second, framing climate justice in terms of political responsibility for unjust structural processes better orients and motivates the political action necessary for structural transformation. (shrink)

How should responsibility be theorized in the context of the global climate crisis? This question is often framed through the language of distributive justice. Because of the inequitable distributi...

A regularity theory of causation analyses type-level causation in terms of Boolean difference-making. The essential ingredient that helps this theoretical framework overcome the problems of Hume’s and Mill’s classical accounts is a principle of non-redundancy: only Boolean dependency structures from which no elements can be eliminated track causation. The first part of this article argues that the recent regularity-theoretic literature has not consistently implemented this principle, for it disregarded an important type of redundancies: structural redundancies. Moreover, it is shown that (...) a regularity theory needs to be underwritten by a hitherto neglected metaphysical background assumption stipulating that the world’s causal makeup is not ambiguous. Against that background, the second part then develops a new regularity theory that does justice to all types of redundancies and, thereby, provides the first all-inclusive notion of Boolean difference-making. (shrink)

The last thirty years have seen a resurgence of interest in virtue among philosophers, psychologists, and educators. This co-authored book brings an interdisciplinary response to the study of virtue: it not only provides a framework for quantifying virtues, but also explores how we can understand virtue in a philosophically-informed way that is compatible with the best current thinking in personality psychology. The volume presents a major contribution to theemerging science of virtue and character measurement.

In the human quest for meaning, work occupies a central position. Most adults spend the majority of their waking hours at work, which often serves as a primary source of purpose, belongingness, and identity. In light of these benefits to employees and their organizations, organizational scholars are increasingly interested in understanding the factors that contribute to meaningful work, such as the design of jobs, interpersonal relationships, and organizational missions and cultures. In a separate line of inquiry, scholars of business ethics (...) have examined meaningful work as a moral issue concerning the management of others and ourselves, exploring whether there are definable characteristics of meaningful work to which we have moral rights, and whether there are moral duties to ourselves and others to fulfill those rights. In this article, we examine contemporary developments in both disciplines about the nature, causes, and consequences of meaningful work; we explore linkages between these disciplines; and we offer conclusions and research opportunities regarding the interface of ethical and organizational perspectives on performing and providing meaningful work. (shrink)

Determinacy axioms state the existence of winning strategies for infinite games played by two players on natural numbers. We show that a base theory enriched by a certain scheme of determinacy axioms is proof-theoretically equivalent to -comprehension.

Quillen [17] introduced model categories as an abstract framework for homotopy theory which would apply to a wide range of mathematical settings. By all accounts this program has been a success and—as, e.g., the work of Voevodsky on the homotopy theory of schemes [15] or the work of Joyal [11, 12] and Lurie [13] on quasicategories seem to indicate—it will likely continue to facilitate mathematical advances. In this paper we present a novel connection between model categories and mathematical logic, inspired (...) by the groupoid model of (intensional) Martin–Löf type theory [14] due to Hofmann and Streicher [9]. In particular, we show that a form of Martin–Löf type theory can be soundly modelled in any model category. This result indicates moreover that any model category has an associated “internal language” which is itself a form of Martin-Löf type theory. This suggests applications both to type theory and to homotopy theory. Because Martin–Löf type theory is, in one form or another, the theoretical basis for many of the computer proof assistants currently in use, such as Coq and Agda (cf. [3] and [5]), this promise of applications is of a practical, as well as theoretical, nature. This paper provides a precise indication of this connection between homotopy theory and logic; a more detailed discussion of these and further results will be given in [20]. (shrink)

In science, it sometimes occurs that an event is directly observed, and on other occasions that it is not directly observed but one can make the unambiguous inference that it has occurred. Is there any difference concerning the analysis of data arising from these two situations? In this note we show that there is such a difference in one case arising frequently in genetics. The difference derives from the fact that the ability to make the unambiguous inference arises only from (...) a restricted form of data. (shrink)

Societal pressures, accreditation organizations, and licensing agencies are emphasizing the importance of ethics in the engineering curriculum. Traditionally, this subject has been taught using dogma, heuristics, and case study approaches. Most recently a number of organizations have sought to increase the utility of these approaches by utilizing the Internet. Resources from these organizations include on-line courses and tests, videos, and DVDs. While these individual approaches provide a foundation on which to base engineering ethics, they may be limited in developing a (...) student’s ability to identify, analyze, and respond to engineering ethics situations outside of the classroom environment. More effective approaches utilize a combination of these types of approaches. This paper describes the design and development of an internet based interactive Simulator for Engineering Ethics Education. The simulator places students in first person perspective scenarios involving different types of ethical situations. Students must gather data, assess the situation, and make decisions. This requires students to develop their own ability to identify and respond to ethical engineering situations. A limited comparison between the internet based interactive simulator and conventional internet web based instruction indicates a statistically significant improvement of 32% in instructional effectiveness. The simulator is currently being used at the University of Houston to help fulfill ABET requirements. (shrink)

A recent American Academy of Pediatrics (AAP) clinical report states that it is an acceptable option for pediatric care clinicians to dismiss families who refuse vaccines. This is a clear shift in guidance from the AAP, which previously advised clinicians to “endeavor not to discharge” patients solely because of parental vaccine refusal. While this new policy might be interpreted as encouraging or recommending dismissal of vaccine-refusing families, it instead expresses tolerance for diverse professional approaches. This is unlike the earlier guidance, (...) which promoted a unified response to vaccine refusal. In fact, the resolution (which was presented at the AAP’s Annual Leadership Forum) that led to this clinical report also calls on the AAP “to continue to support pediatricians who continue to provide health care to children of parents who refuse to immunize their children.” However, the shift toward embracing dismissal as an acceptable response to vaccine refusal may erode professional solidarity. Pediatricians are clearly divided on this question; most do not dismiss vaccine-refusing families. By declaring that dismissal is an acceptable option, the AAP has sanctioned a practice that may be unfair to the many clinicians who do not dismiss these families. Clinicians who adopt a policy of dismissal toward families who refuse vaccines might impose burdens on colleagues who remain willing to offer care to those families, and their actions might show insufficient commitment to the efforts of their profession to promote health for all children. (shrink)

Deep brain stimulation is a well-established therapy for the motor symptoms of Parkinson’s disease, but there remains an opportunity to improve symptom relief. The temporal pattern of stimulation is a new parameter to consider in DBS therapy, and we compared the effectiveness of Temporally Optimized Patterned Stimulation to standard DBS at reducing the motor symptoms of PD. Twenty-six subjects with DBS for PD received three different patterns of stimulation while on medication and using stimulation parameters optimized for standard DBS. Side (...) effects and motor symptoms were assessed after 30 min of stimulation with each pattern. Subjects experienced similar types of side effects with TOPS and standard DBS, and TOPS were well-tolerated by a majority of the subjects. On average, the most effective TOPS was as effective as standard DBS at reducing the motor symptoms of PD. In some subjects a TOPS pattern was the most effective pattern. Finally, the TOPS pattern with low average frequency was found to be as effective or more effective in about half the subjects while substantially reducing estimated stimulation energy use. TOPS DBS may provide a new programing option to improve DBS therapy for PD by improving symptom reduction and/or increasing energy efficiency. Optimizing stimulation parameters specifically for TOPS DBS may demonstrate further clinical benefit of TOPS DBS in treating the motor symptoms of Parkinson’s disease. (shrink)

In this paper the machinery and results developed in [Awodey et al, 2004] are extended to the study of constructive set theories. Specifically, we introduce two constructive set theories BCST and CST and prove that they are sound and complete with respect to models in categories with certain structure. Specifically, basic categories of classes and categories of classes are axiomatized and shown to provide models of the aforementioned set theories. Finally, models of these theories are constructed in the category of (...) ideals. (shrink)

The Process Specification Language (PSL) has been designed to facilitate correct and complete exchange of process information among manufacturing systems, such as scheduling, process modeling, process planning, production planning, simulation, project management, work flow, and business process reengineering. We given an overview of the theories with the PSL ontology, discuss some of the design principles for the ontology, and finish with examples of process specifications that are based on the ontology.

BackgroundThe SARS-CoV-2 pandemic has highlighted once more the great need for comprehensive access to, and uncomplicated use of, pre-existing patient data for medical research. Enabling secondary research-use of patient-data is a prerequisite for the efficient and sustainable promotion of translation and personalisation in medicine, and for the advancement of public-health. However, balancing the legitimate interests of scientists in broad and unrestricted data-access and the demand for individual autonomy, privacy and social justice is a great challenge for patient-based medical research.MethodsWe therefore (...) conducted two questionnaire-based surveys among North-German outpatients (n = 650) to determine their attitude towards data-donation for medical research, implemented as an opt-out-process.ResultsWe observed a high level of acceptance (75.0%), the most powerful predictor of a positive attitude towards data-donation was the conviction that every citizen has a duty to contribute to the improvement of medical research (> 80% of participants approving data-donation). Interestingly, patients distinguished sharply between research inside and outside the EU, despite a general awareness that universities and public research institutions cooperate with commercial companies, willingness to allow use of donated data by the latter was very low (7.1% to 29.1%, depending upon location of company). The most popular measures among interviewees to counteract reservations against commercial data-use were regulation by law (61.4%), stipulating in the process that data are not sold or resold (84.6%). A majority requested control of both the use (46.8%) and the protection (41.5%) of the data by independent bodies.ConclusionsIn conclusion, data-donation for medical research, implemented as a combination of legal entitlement and easy-to-exercise-right to opt-out, was found to be widely supported by German patients and therefore warrants further consideration for a transposition into national law. (shrink)

As organizations take on grand challenges in gender equality, anti-racism, LGBTQ+ protections and workplace inclusion, many well-intentioned individuals from dominant groups (e.g., cisgender men, Caucasian, heterosexual) are stepping forward as allies toward underrepresented or marginalized group members (e.g., cisgender women, People of Color, LGBTQ+ identified employees). Past research and guidance assume an inevitable need for external motivation, reflected in the ‘business case’ for diversity and in top-down policies to drive equity and inclusion efforts. This qualitative study explored _internal_ motivations in (...) the form of morally motivated virtues of 25 peer-nominated exemplary allies serving in leadership positions. In-depth life/career story interviews were used to identify the virtues that supported their allyship journeys. Findings demonstrated that they tapped into several virtues that served distinct functions in a 4-stage allyship development process: Stage 1—Energizing psychological investment (compassion, fairness); Stage 2—Thinking through allyship-relevant complexities (intellectual humility, perspective-taking, wisdom); Stage 3—Initiating action (prudence, moral courage, honesty); Stage 4—Committing to allyship (perseverance, patience). We call this the ‘EThIC model of virtue-based allyship development.’ This study has implications for theory and research on a virtue-based approach to diversity, equity and inclusion. (shrink)